Publications

Type
Date
Drug Discovery
2019-10
Magnetic Resonance Imaging of Knee Joint Protection Following an Intra-Articular Injection of Lipid-Based Dexamethasone Sodium Phosphate Sustained Release Formulation on Subjects with Knee Osteoarthritis
Author(s) Sheue-Fang Shih, Carl Brown, Tien-Tzu Tai and Wing Chuang; Taiwan Liposome Company (TLC), Ltd., Taipei, Taiwan
Published
Drug Discovery
2019-10
A Phase 1/2, Randomized, Double-blind, Comparator-controlled, Dose-escalation Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of TLC590 for Postsurgical Pain Management following Inguinal Hernia Repair
Author(s) Todd M. Bertoch, Carl O. Brown, Chih-Feng Wu, Pei-Hsien Hu, Tien-Tzu Tai, Weenee Y. N. Jao, Cheng-Yu Kuo, Hui-Ting Wang, Min-Wen, Kuo, Yun-Long Tseng, JBR Clinical Research, Salt Lake City, UT, USA and Taiwan Liposome Company (TLC), Taipei City, Taiwan
Published
Drug Discovery
2019-10
Formulation and Evaluation of Multilamellar Vesicles Ropivacaine in Pain Management
Author(s) Hao-Wen Kao, Yi-Yu Lin, Walter J Gwathney, Keelung Hong, TLC Biopharmaceuticals, Inc., South San Francisco, CA 94080, USA; Taiwan Liposome Company, Ltd., Taipei 11503, Taiwan
Published
Drug Discovery
2019-09
In Vivo Efficacy and Enhanced Tumor Accumulation of Liposomal Vinorelbine (TLC178) in Human Sarcoma Xenograft Mouse Models
Author(s) Wan-Ni. Yu, Jo-Hsin Tang, Tzung-Ju Wu, Yi-Chen Tsai and Hui-Ting Wang; Non-clinical Department, Pharmacokinetic Department, Taiwan Liposome Company, Taipei City, Taiwan
Published
Drug Discovery
2019-06
Pharmacokinetic and Toxicokinetic Studies of a Sustained Release Liposomal Formulation of Dexamethasone Sodium Phosphate (TLC599) Following Intra-articular Injection in Dogs
Author(s) Tzung-Ju Wu, Wan-Ni. Yu, Ming-Ju Wu, Po-Chun Chang, Hui-Ting Wang and Sheue-Fang Shih; Taiwan Liposome Company, Taipei, Taiwan
Published European Congress of Rheumatology (EULAR 2019)
Drug Discovery
2019-05
Cartilage Damage and Synovial Toxicokinetic Study of a Sustained Release Liposomal Formulation of Dexamethasone Sodium Phosphate (TLC599) following Intra-articular Injection in Healthy Dogs and Rabbits
Author(s) W-N. Yu, M-J Wu, P-C Chang, S-F Shih; Taiwan Liposome Company, Taipei, Taiwan
Published 2019 OARSI World Congress on Osteoarthritis
Drug Discovery
2019-05
Single Intra-articular Injection of TLC599 Provided Sustained Pain Relief through 24 Weeks in Participants with Symptomatic Knee Osteoarthritis
Author(s) D. Hunter, C-C. Chang, J-C. Wei, H-Y. Lin, C. Brown, S-F. Shih; Univ. of Sydney, Sydney, Australia, Royal North Shore Hosp., Sydney, Australia, Div. of Allergy, Immunology and Rheumatology, Dept. of Internal Med., Sch. of Med., Coll. of Med., Taipei Med. Univ., Taipei, Taiwan, Div. of Allergy, Immunology and
Rheumatology, Chung Shan Med. Univ. Hosp., Taipei, Taiwan, Dept. of Internal Med., Cheng Hsin Gen. Hosp., Taipei,
Taiwan, Dept. of Allergy, Immunology and Rheumatology, Taipei Veterans Gen. Hosp., Taipei, Taiwan, Taiwan
Liposome Company, Taipei, Taiwan
Published 2019 OARSI World Congress on Osteoarthritis
Drug Discovery
2018-09
Safety, Tolerability, and Efficacy of a Novel Sustained-release Liposomal Formulation of Dexamethasone Sodium Phosphate (TLC599) in Patients with Knee Osteoarthritis
Author(s) Chien-Chih Lai, Chao-Ching Chiang, Chyou-Shen Lee, Chi-Ching Chang, Hsiao-Yi Lin, Tien-Ling Chen, and Sheue-Fang Shih
Published 20th Asia Pacific League of Associations for Rheumatology Congress
Oncology
Delivery Technology
2014-12
One-step Mixing with Humanized Anti-mPEG Bispecific Antibody Enhances Tumor Accumulation and Therapeutic Efficacy of mPEGylated Nanoparticles
Author(s) Kao C. H., Wang J. Y., Chuang K. H., Chuang C. H., Cheng T. C., Hsieh Y. C., Tseng Y. L., Chen B. M., Roffler S. R., Cheng T. L.
Published Biomaterials.
(37):9930-40, 2014.
Oncology
Clinical Development
2014-06
A Phase I Open-label, Sequential Dose-escalation Study Investigating the Safety, Tolerability, and Pharmacokinetics of Intravenous TLC388 Administered to Patients with Advanced Solid Tumors
Author(s) Ghamande, S., Lin, C. C., Cho, D. C., Shapiro, G. I., Kwak, E. L., Silverman, M. H., Tseng, Y. L., Kuo, M. W., Mach, W. B., Hsu, S. C., Coleman, T., Yang, J. C., Cheng, A. L., Ghalib, M. H., Chuadhary, I., Goel, S.
Published Invest New Drugs.
32(3):445-51, 2014.
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