LipAD™ - Proprietary Lipid-Assembled Drug Delivery Platforms
TLC is committed to creating solutions for longstanding challenges in drug development by enabling new therapies with entirely unique properties.
Passive Targeting: Increasing Time in Circulation with NanoX™
Many drugs are quickly degraded once they enter the body. TLC uses NanoX™ technology to efficiently encapsulate drugs of many different molecular subtypes within lipid nanoparticles. This protects fragile drugs from enzymatic degradation or changes in pH. With prolonged time in circulation, a drug is more likely to reach specific disease sites such as tumors characterized by increased vascular permeability.More on NanoX™
Active Targeting: Using Antibodies to Deliver Drugs to Specific Tissues
Attaching antibodies or antibody fragments to lipid-encapsulated drug nanoparticles can be used to direct a payload to a particular tissue type in the body. This allows nanoparticles to accumulate at a specific site in the body, delivering a drug to where it is needed while avoiding other tissues. Once at the correct location, lipids help bring the drug inside of the cell to take effect.More on Antibody-Linked Nanomedicines